Alain de Bruin

An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA

Marco Demaria, Naoko Ohtani, Sameh A. Youssef et al. · Developmental Cell · 2014 · 2K citations · Full text

Life Sciences, Cell Biology, Cell Signaling +10

Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse

Marco Demaria, Monique N. O’Leary, Jianhui Chang et al. · Cancer Discovery · 2016 · 1.3K citations · Full text

Medicine, Cancer Biology, Cancer Pharmacology +15

Extra-embryonic function of Rb is essential for embryonic development and viability

Lizhao Wu, Alain de Bruin, Harold I. Saavedra et al. · Nature · 2003 · 385 citations

Life Sciences, Developmental Biology, Genetics +9

A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis

Eelke Brandsma, Niels Kloosterhuis, Mirjam H. Koster et al. · Circulation Research · 2019 · 376 citations · Full text

Life Sciences, Immunology, Microbiology +12

Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer

Anthony J. Trimboli, Koichi Fukino, Alain de Bruin et al. · Cancer Research · 2008 · 359 citations · Full text

Medicine, Cell Biology, Oncology +17