New mechanism of neuroinflammation in Alzheimer's disease: The activation of NLRP3 inflammasome mediated by gut microbiota

Heping Shen, Qiaobing Guan, Xiaoling Zhang, +6

Progress in Neuro-Psychopharmacology and Biological Psychiatry

ImmunologyGut MicrobiotaNeuroinflammationInflammationAlzheimer's Disease +14

ADMSC Exo‐MicroRNA‐22 improve neurological function and neuroinflammation in mice with Alzheimer's disease

Liping Zhai, Heping Shen, Yongjia Sheng, +1

Journal of Cellular and Molecular Medicine

Pyroptosis executive protein GSDMD as a biomarker for diagnosis and identification of Alzheimer’s disease

Heping Shen, Chenyang Han, Yi Yang, +7

Brain and Behavior

Anticonvulsant and anti-apoptosis effects of salvianolic acid B on pentylenetetrazole-kindled rats via AKT/CREB/BDNF signaling

Xiaoxiang Yu, Qiaobing Guan, Yanping Wang, +4

Epilepsy Research

Sal BCell DeathPharmacotherapyNeural DensityExperimental Pharmacology +17

Salvianolic acid C improves cerebral ischemia reperfusion injury through suppressing microglial cell M1 polarization and promoting cerebral angiogenesis

Heping Shen, Hongyan Pei, Liping Zhai, +2

International Immunopharmacology

Salvianolic Acid CCerebral AngiogenesisCerebral Vascular RegulationOxidative StressInflammation +14

Antrodia camphorata polysaccharide resists 6‐OHDA‐induced dopaminergic neuronal damage by inhibiting ROS‐NLRP3 activation

Chenyang Han, Heping Shen, Yi Yang, +7

Brain and Behavior

Spatial–temporal signature of resting-state BOLD signals in classic trigeminal neuralgia

Yanping Wang, Congying Xu, Liping Zhai, +6

Journal of Pain Research

Paeoniflorin suppresses neuronal ferroptosis to improve the cognitive behaviors in Alzheimer's disease mice

Liping Zhai, Hongyan Pei, Heping Shen, +3

Phytotherapy Research

Neurochemical BiomarkersAd MiceRedox BiologyFerroptosisOxidative Stress +16

Gastrodin improves nerve cell injury and behaviors of depressed mice through Caspase‐3‐mediated apoptosis

Hongyan Pei, Heping Shen, Jinhao Bi, +2

CNS Neuroscience & Therapeutics

Network PharmacologySynaptic TransmissionApoptosisNeurotransmitterCell Death +20

Advanced Glycation End-Products (AGEs) Promote Endothelial Cell Pyroptosis Under Cerebral Ischemia and Hypoxia via HIF-1α-RAGE-NLRP3

Chenyang Han, Liping Zhai, Heping Shen, +2

Molecular Neurobiology

Endothelial Cell PathobiologyCerebral IschemiaPhysiologyHypoxia (Medicine)Endothelial Dysfunction +8