Manuel Köckinger

Design and 3D printing of a stainless steel reactor for continuous difluoromethylations using fluoroform

Bernhard Gutmann, Manuel Köckinger, Gabriel Glotz et al. · Reaction Chemistry & Engineering · 2017 · 94 citations · Full text

Engineering, Chemical Engineering, Chemistry +9

Utilization of fluoroform for difluoromethylation in continuous flow: a concise synthesis of α-difluoromethyl-amino acids

Manuel Köckinger, Tanja Ciaglia, Michaël Bersier et al. · Green Chemistry · 2017 · 57 citations · Full text

Engineering, Chemical Engineering, Medicinal Chemistry +10

Scalable Continuous Flow Process for the Synthesis of Eflornithine Using Fluoroform as Difluoromethyl Source

Manuel Köckinger, Christopher A. Hone, Bernhard Gutmann et al. · Organic Process Research & Development · 2018 · 45 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

Blockage of Store-Operated Ca2+ Influx by Synta66 is Mediated by Direct Inhibition of the Ca2+ Selective Orai1 Pore

Linda Waldherr, Adéla Tiffner, Deepti Mishra et al. · Cancers · 2020 · 41 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Optimization and Scale-Up of the Continuous Flow Acetylation and Nitration of 4-Fluoro-2-methoxyaniline to Prepare a Key Building Block of Osimertinib

Manuel Köckinger, Benjamin Wyler, Christof Aellig et al. · Organic Process Research & Development · 2020 · 40 citations · Full text

Medicine, Medicinal Chemistry, Oncology +12