Oscar A. MacLean

SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Brian J. Willett, Joe Grove, Oscar A. MacLean et al. · Nature Microbiology · 2022 · 701 citations · Full text

The emergence and ongoing convergent evolution of the SARS-CoV-2 N501Y lineages

Darren P. Martin, Steven Weaver, Houriiyah Tegally et al. · Cell · 2021 · 267 citations · Full text

Viral Evolution, Virus Phylogeny, Ongoing Convergent Evolution +4

Natural selection in the evolution of SARS-CoV-2 in bats created a generalist virus and highly capable human pathogen

Oscar A. MacLean, Spyros Lytras, Steven Weaver et al. · PLoS Biology · 2021 · 219 citations · Full text

Viral Pathogenesis, Natural Selection, Virus Transmission +18

In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2

Agnieszka M. Szemiel, Andres Merits, Richard Orton et al. · PLoS Pathogens · 2021 · 158 citations · Full text

Remdesivir Resistance, Rdv Sensitivity, Viral Replication +15

The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism

Brian J. Willett, Joe Grove, Oscar A. MacLean et al. · 2022 · 144 citations · Full text

Vaccination, Spike Protein, Vaccine Development +14