Secondary structural ensembles of the SARS-CoV-2 RNA genome in infected cells

Tammy C. T. Lan, Matthew F. Allan, Lauren E. Malsick, +11

Nature Communications

A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer

Chi Zhu, Li Li, Zhao Zhang, +10

Molecular Cell

Yap/tead Is RequiredBreast OncologyHormonal ReceptorBreast CancerCell Biology +6

An intranasal ASO therapeutic targeting SARS-CoV-2

Chi Zhu, Justin Y. Lee, Jia Z. Woo, +19

Nature Communications

A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion

Tsuneo Ikenoue, Yumi Terakado, Hayato Nakagawa, +15

Scientific Reports

SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling

Scott B. Biering, Francielle Tramontini Gomes de Sousa, Laurentia V. Tjang, +26

Nature Communications

Anti-apoptotic effect by the suppression of IRF1 as a downstream of Wnt/β-catenin signaling in colorectal cancer cells

Tomoyuki Ohsugi, Kiyoshi Yamaguchi, Chi Zhu, +6

Oncogene

Cancer ResearchAnti-apoptotic EffectSignaling PathwayMedicineColorectal Cancer +9

Decreased expression of interferon-induced protein 2 (IFIT2) by Wnt/β-catenin signaling confers anti-apoptotic properties to colorectal cancer cells

Tomoyuki Ohsugi, Kiyoshi Yamaguchi, Chi Zhu, +2

Oncotarget

Cancer-associated IDH mutations induce Glut1 expression and glucose metabolic disorders through a PI3K/Akt/mTORC1-Hif1α axis

Xun Liu, Kiyoshi Yamaguchi, Kiyoko Takane, +6

PLoS ONE

An intranasal ASO therapeutic targeting SARS-CoV-2

Chi Zhu, Justin Y. Lee, Jia Z. Woo, +18

Viral ReplicationLna AsosViral PathogenesisImmunologyImmunodominance +14

Bidirectional reporter assay using <i>HAL</i> promoter and TOPFLASH improves specificity in high‐throughput screening of Wnt inhibitors

Kiyoshi Yamaguchi, Chi Zhu, Tomoyuki Ohsugi, +3

Biotechnology and Bioengineering