Mary E. Fox

Anaerobic bacteria as a delivery system for cancer gene therapy: in vitro activation of 5-fluorocytosine by genetically engineered clostridia.

Mary E. Fox, Marilyn J. Lemmon, Margaret L. Mauchline et al. · PubMed · 1996 · 172 citations

Long-term inhibition of DNA synthesis and the persistence of trapped topoisomerase II complexes in determining the toxicity of the antitumor DNA intercalators mAMSA and mitoxantrone.

Mary E. Fox, Peter J. Smith · PubMed · 1990 · 83 citations

Molecular Biology, Topoisomerase Ii Trapping, Dna Intercalators +17

Mitoxantrone-DNA binding and the induction of topoisomerase II associated DNA damage in multi-drug resistant small cell lung cancer cells

Paul J. Smith, Sally A. Morgan, Mary E. Fox et al. · Biochemical Pharmacology · 1990 · 70 citations

Mitoxantrone-dna Binding, Dna Damage, Oncogenic Agent +10

Subcellular distribution of the anticancer drug mitoxantrone in human and drug-resistant murine cells analyzed by flow cytometry and confocal microscopy and its relationship to the induction of DNA damage.

Paula Smith, Hazel Sykes, Mary E. Fox et al. · PubMed · 1992 · 56 citations

Engineering, Oncologic Imaging, Intense Intranuclear Fluorescence +18

A Novel Role for DNA Photolyase: Binding to DNA Damaged by Drugs Is Associated with Enhanced Cytotoxicity in <i>Saccharomyces cerevisiae</i>

Mary E. Fox, Brian J. Feldman, Gilbert Chu · Molecular and Cellular Biology · 1994 · 47 citations · Full text

Genome Instability, Dna Damage, Uv Radiation +13