A live attenuated virus-based intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2

Junyu Chen, Pui Wang, Lunzhi Yuan, +33

Science Bulletin

A recombinant spike protein subunit vaccine confers protective immunity against SARS-CoV-2 infection and transmission in hamsters

Yangtao Wu, Xiaofen Huang, Lunzhi Yuan, +33

Science Translational Medicine

Combination therapy with oncolytic virus and T cells or mRNA vaccine amplifies antitumor effects

Rao Fu, Ruoyao Qi, Hualong Xiong, +24

Signal Transduction and Targeted Therapy

Intranasal influenza-vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response in hamsters

Liang Zhang, Yao Jiang, Jinhang He, +39

Nature Communications

A unique B cell epitope-based particulate vaccine shows effective suppression of hepatitis B surface antigen in mice

Tianying Zhang, Xueran Guo, Yangtao Wu, +24

Gut

The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2

Hualong Xiong, Hui Sun, Siling Wang, +28

Proceedings of the National Academy of Sciences

VaccinationUndiminished NeutralizationViral DiagnosticsVaccine TargetNeutralizing Breadth +13

Therapeutic vaccine-induced plasma cell differentiation is defective in the presence of persistently high HBsAg levels

Ruoyao Qi, Rao Fu, Lei Xing, +27

Journal of Hepatology

A broad-spectrum nanobody targeting the C-terminus of the hepatitis B surface antigen for chronic hepatitis B infection therapy

Yue Wang, Yaxian Mei, Zhenghong Ao, +11

Antiviral Research

NanoparticlesEngineeringImmunologyHepatitis BSustainable Viral Suppression +20

The potential of swine pseudorabies virus attenuated vaccine for oncolytic therapy against malignant tumors

Guosong Wang, Jiali Cao, Mengxuan Gui, +21

Journal of Experimental & Clinical Cancer Research