Eva Große Maestrup

Molecular imaging of σ receptors: synthesis and evaluation of the potent σ1 selective radioligand [18F]fluspidine

Steffen Fischer, Christian Wiese, Eva Große Maestrup et al. · European Journal of Nuclear Medicine and Molecular Imaging · 2010 · 66 citations

Molecular Pharmacology, Biochemistry, Medicine +10

Evaluation of Spirocyclic 3-(3-Fluoropropyl)-2-benzofurans as σ₁ Receptor Ligands for Neuroimaging with Positron Emission Tomography

Eva Große Maestrup, Steffen Fischer, Christian Wiese et al. · Journal of Medicinal Chemistry · 2009 · 50 citations · Full text

Combinatorial Chemistry, Radiotracer Properties, Chemical Biology +22

Synthesis, pharmacological activity and structure affinity relationships of spirocyclic σ1 receptor ligands with a (2-fluoroethyl) residue in 3-position

Eva Große Maestrup, Christian Wiese, Dirk Schepmann et al. · Bioorganic & Medicinal Chemistry · 2010 · 45 citations · Full text

Molecular Pharmacology, Drug Target, Biochemistry +9

Synthesis of spirocyclic σ1 receptor ligands as potential PET radiotracers, structure–affinity relationships and in vitro metabolic stability

Eva Große Maestrup, Christian Wiese, Dirk Schepmann et al. · Bioorganic & Medicinal Chemistry · 2009 · 36 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8

Pharmacological and metabolic characterisation of the potent σ1 receptor ligand 1′-benzyl-3-methoxy-3H-spiro[[2]benzofuran-1,4′-piperidine]

Christian Wiese, Eva Große Maestrup, Dirk Schepmann et al. · Journal of Pharmacy and Pharmacology · 2009 · 31 citations