William D. Klaren

PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats

Gopi S. Gadupudi, William D. Klaren, Alicia K. Olivier et al. · Toxicological Sciences · 2015 · 84 citations · Full text

Cardiovascular Effects of Polychlorinated Biphenyls and Their Major Metabolites

Fabian A. Grimm, William D. Klaren, Xueshu Li et al. · Environmental Health Perspectives · 2020 · 61 citations · Full text

Machine Learning Models for Estrogen Receptor Bioactivity and Endocrine Disruption Prediction

Kimberley M. Zorn, Daniel H. Foil, Thomas R. Lane et al. · Environmental Science & Technology · 2020 · 49 citations · Full text

Predictive modeling of biological responses in the rat liver using in vitro Tox21 bioactivity: Benefits from high-throughput toxicokinetics

Caroline Ring, Nisha S. Sipes, Jui‐Hua Hsieh et al. · Computational Toxicology · 2021 · 41 citations · Full text

Identifying Attributes That Influence<i>In Vitro</i>-to-<i>In Vivo</i>Concordance by Comparing<i>In Vitro</i>Tox21 Bioactivity Versus<i>In Vivo</i>DrugMatrix Transcriptomic Responses Across 130 Chemicals

William D. Klaren, Caroline Ring, Mark Anglin Harris et al. · Toxicological Sciences · 2018 · 36 citations · Full text

Gene Expression Profiling, Biological Significance, Systems Pharmacology +30