Héctor de Lucio

Synthesis and Leishmanicidal Activity of Novel Urea, Thiourea, and Selenourea Derivatives of Diselenides

Marta Díaz, Héctor de Lucio, Esther Moreno et al. · Antimicrobial Agents and Chemotherapy · 2019 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of <i>Leishmania infantum</i> Trypanothione Reductase

Alejandro Revuelto, Marta Ruiz‐Santaquiteria, Héctor de Lucio et al. · ACS Infectious Diseases · 2019 · 37 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity #

Marta Ruiz‐Santaquiteria, Pedro A. Sánchez‐Murcia, Miguel Toro-Londoño et al. · European Journal of Medicinal Chemistry · 2017 · 33 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +17

Efficient Dimerization Disruption of <i>Leishmania infantum</i> Trypanothione Reductase by Triazole-phenyl-thiazoles

Alejandro Revuelto, Héctor de Lucio, Juan Carlos García-Soriano et al. · Journal of Medicinal Chemistry · 2021 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Trypanothione reductase inhibition and anti-leishmanial activity of all-hydrocarbon stapled α-helical peptides with improved proteolytic stability

Marta Ruiz‐Santaquiteria, Sonia de Castro, Miguel Toro-Londoño et al. · European Journal of Medicinal Chemistry · 2018 · 19 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17