Austin B. Souryavong

A new thiol-independent mechanism of epithelial host defense against Pseudomonas aeruginosa: iNOS/NO• sabotage of theft-ferroptosis

Haider H. Dar, Tamil S. Anthonymuthu, Liubov A. Ponomareva et al. · Redox Biology · 2021 · 87 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Strikingly High Activity of 15‐Lipoxygenase Towards Di‐Polyunsaturated Arachidonoyl/Adrenoyl‐Phosphatidylethanolamines Generates Peroxidation Signals of Ferroptotic Cell Death

Svetlana N. Samovich, Karolina Mikulska‐Ruminska, Haider H. Dar et al. · Angewandte Chemie International Edition · 2024 · 51 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

P. aeruginosa augments irradiation injury via 15-lipoxygenase–catalyzed generation of 15-HpETE-PE and induction of theft-ferroptosis

Haider H. Dar, Michael W. Epperly, Vladimir A. Tyurin et al. · JCI Insight · 2022 · 45 citations · Full text

Life Sciences, Immunology, Microbiology +17

Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators

Haider H. Dar, Karolina Mikulska‐Ruminska, Yulia Y. Tyurina et al. · Proceedings of the National Academy of Sciences · 2023 · 27 citations · Full text

Life Sciences, Cell Biology, Pharmacology +14

Anomalous peroxidase activity of cytochrome c is the primary pathogenic target in Barth syndrome

Valerian E. Kagan, Yulia Y. Tyurina, Karolina Mikulska‐Ruminska et al. · Nature Metabolism · 2023 · 22 citations · Full text

Life Sciences, Biochemistry, Pathobiology +4