Simran S. Sabharwal

Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide

Olesya A. Ulanovskaya, Jelena M. Janjic, Masato Suzuki et al. · Nature Chemical Biology · 2008 · 94 citations · Full text

Molecular Biological Method, Medicine, Molecular Biology +7

The Selective Protein Kinase C β Inhibitor Enzastaurin Induces Apoptosis in Cutaneous T-Cell Lymphoma Cell Lines through the AKT Pathway

Christiane Querfeld, Mujahid A. Rizvi, Timothy M. Kuzel et al. · Journal of Investigative Dermatology · 2006 · 88 citations · Full text

Lymphoid Neoplasia, Medicine, Immunology +7

Peroxiredoxin-5 targeted to the mitochondrial intermembrane space attenuates hypoxia-induced reactive oxygen species signalling

Simran S. Sabharwal, Gregory B. Waypa, Jeremy D. Marks et al. · Biochemical Journal · 2013 · 60 citations · Full text

Ims-prdx5 Expression, Redox Biology, Cellular Physiology +17

GITR Agonism Enhances Cellular Metabolism to Support CD8+ T-cell Proliferation and Effector Cytokine Production in a Mouse Tumor Model

Simran S. Sabharwal, David B. Rosen, Jeff Grein et al. · Cancer Immunology Research · 2018 · 55 citations

TransCon IL-2 β/γ: a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 variant with improved pharmacokinetics and potent activation of cytotoxic immune cells for the treatment of cancer

David B. Rosen, Anne Månsson Kvarnhammar, Burkhardt Laufer et al. · Journal for ImmunoTherapy of Cancer · 2022 · 34 citations · Full text