Guolin Shen

Role of CYP3A in regulating hepatic clearance and hepatotoxicity of triptolide in rat liver microsomes and sandwich-cultured hepatocytes

Guolin Shen, Xiaomei Zhuang, Weibin Xiao et al. · Food and Chemical Toxicology · 2014 · 45 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Metabonomics reveals that triclocarban affects liver metabolism by affecting glucose metabolism, β-oxidation of fatty acids, and the TCA cycle in male mice

Wentao Li, Wenpeng Zhang, Mengyang Chang et al. · Toxicology Letters · 2018 · 44 citations

Life Sciences, Biochemistry, Cellular Metabolism +14

Tributyl phosphate impairs the urea cycle and alters liver pathology and metabolism in mice after short-term exposure based on a metabonomics study

Lili Zhou, Wenpeng Zhang, Wenping Xie et al. · The Science of The Total Environment · 2017 · 42 citations

Life Sciences, Biochemistry, Toxicology +13

Assessment of the Roles of P-glycoprotein and Cytochrome P450 in Triptolide-induced Liver Toxicity in Sandwich-Cultured Rat Hepatocyte Model

Xiaomei Zhuang, Guolin Shen, Weibin Xiao et al. · Drug Metabolism and Disposition · 2013 · 41 citations

Pharmacy, Pharmacology, Toxicology +17

Characterization of human metabolism and disposition of levo-tetrahydropalmatine: Qualitative and quantitative determination of oxidative and conjugated metabolites

Weibin Xiao, Guolin Shen, Xiaomei Zhuang et al. · Journal of Pharmaceutical and Biomedical Analysis · 2016 · 21 citations

Life Sciences, Pharmacokinetics, Pharmacology +11