Patrick Alexander

A minimal sequence code for switching protein structure and function

Patrick Alexander, Yanan He, Yihong Chen et al. · Proceedings of the National Academy of Sciences · 2009 · 273 citations · Full text

Protein Assembly, Biomolecular Structure Prediction, Structural Bioinformatics +20

Gene for an immunoglobulin-binding protein from a group G streptococcus

Stephen R. Fahnestock, Patrick Alexander, James W. Nagle et al. · Journal of Bacteriology · 1986 · 241 citations · Full text

Immunoglobulin-binding Protein, Protein Expression, Medicine +14

The design and characterization of two proteins with 88% sequence identity but different structure and function

Patrick Alexander, Yanan He, Yihong Chen et al. · Proceedings of the National Academy of Sciences · 2007 · 199 citations · Full text

Kinetic analysis of folding and unfolding the 56 amino acid IgG-binding domain of streptococcal protein G

Patrick Alexander, John Orban, Philip N. Bryan · Biochemistry · 1992 · 159 citations

Mutational Tipping Points for Switching Protein Folds and Functions

Yanan He, Yihong Chen, Patrick Alexander et al. · Structure · 2012 · 114 citations · Full text

Protein Folding, Natural Sciences, Directed Evolution +5