Robert Holgate

Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex–mediated immune responses

Laurence Blumberg, James E. Humphries, Susan Dana Jones et al. · Science Advances · 2019 · 124 citations · Full text

Life Sciences, Immunology, Clinical Immunology +6

Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury

Anissa A. Widjaja, Jinrui Dong, Eleonora Adami et al. · Science Translational Medicine · 2021 · 73 citations · Full text

Life Sciences, Immunology, Pharmacology +17

The INNs and outs of antibody nonproprietary names

Tim D. Jones, Paul J. Carter, Andreas Plückthun et al. · mAbs · 2015 · 59 citations · Full text

Pharmacy, Biotechnology, Immunology +13

p53 binds the nuclear matrix in normal cells: binding involves the proline-rich domain of p53 and increases following genotoxic stress

Ming Jiang, Tracy Axe, Robert Holgate et al. · Oncogene · 2001 · 47 citations

Life Sciences, Cell Biology, Molecular Biology +14

A variant human IgG1-Fc mediates improved ADCC

Ross Stewart, George Thom, Michaela Levens et al. · Protein Engineering Design and Selection · 2011 · 40 citations · Full text

Pharmacy, Immunology, Molecular Biology +17