Alexandra Westbrook

De novo design of bioactive protein switches

Robert A. Langan, Scott E. Boyken, Andrew H. Ng et al. · Nature · 2019 · 273 citations · Full text

Natural Sciences, Directed Evolution, Molecular Biology +5

Computational design of small transcription activating RNAs for versatile and dynamic gene regulation

James Chappell, Alexandra Westbrook, Matthew S. Verosloff et al. · Nature Communications · 2017 · 150 citations · Full text

Distinct timescales of RNA regulators enable the construction of a genetic pulse generator

Alexandra Westbrook, Xun Tang, Ryan Marshall et al. · Biotechnology and Bioengineering · 2019 · 53 citations · Full text

Engineering, Rna Regulators, Distinct Timescales +28

Mathematical Modeling of RNA-Based Architectures for Closed Loop Control of Gene Expression

Deepak K. Agrawal, Xun Tang, Alexandra Westbrook et al. · ACS Synthetic Biology · 2018 · 51 citations

Engineering, Molecular Biology, Synthetic Circuit +19

Achieving large dynamic range control of gene expression with a compact RNA transcription–translation regulator

Alexandra Westbrook, Julius B. Lucks · Nucleic Acids Research · 2017 · 48 citations · Full text

Incomplete Repression, Engineering, Rna Splicing +19