Sarel F. Malan

Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease

Jacques Joubert, Germaine B. Foka, Benjamin P. Repsold et al. · European Journal of Medicinal Chemistry · 2016 · 128 citations · Full text

Medicinal Chemistry, Neurodegenerative Diseases, Alzheimer's Disease +14

Inhibition of monoamine oxidase by 8-benzyloxycaffeine analogues

Belinda Strydom, Sarel F. Malan, Neal Castagnoli et al. · Bioorganic & Medicinal Chemistry · 2010 · 86 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8

Inhibition of monoamine oxidase B by analogues of the adenosine A2A receptor antagonist (E)-8-(3-chlorostyryl)caffeine (CSC)

Nevil Vlok, Sarel F. Malan, Neal Castagnoli et al. · Bioorganic & Medicinal Chemistry · 2006 · 81 citations

Monoamine Oxidase B, Biochemistry, Medicine +8

Synthesis and biological evaluation of pentacyclo[5.4.0.02,6.03,10.05,9]undecane derivatives as potential therapeutic agents in Parkinson's disease

Werner J. Geldenhuys, Sarel F. Malan, T. Murugesan et al. · Bioorganic & Medicinal Chemistry · 2004 · 74 citations

Medicinal Chemistry, Potential Therapeutic Agents, Heterocyclic +9

Dual inhibition of monoamine oxidase B and antagonism of the adenosine A2A receptor by (E,E)-8-(4-phenylbutadien-1-yl)caffeine analogues

Judey Pretorius, Sarel F. Malan, Neal Castagnoli et al. · Bioorganic & Medicinal Chemistry · 2008 · 74 citations · Full text

Inhibitory Activity, Biochemistry, Dual Inhibition +8