Joseph M. Cicchese

Both Pharmacokinetic Variability and Granuloma Heterogeneity Impact the Ability of the First-Line Antibiotics to Sterilize Tuberculosis Granulomas

Joseph M. Cicchese, Véronique Dartois, Denise E. Kirschner et al. · Frontiers in Pharmacology · 2020 · 39 citations · Full text

Antibiotic Adjuvant, Tuberculosis Prevention, Granuloma Heterogeneity +20

Applying Optimization Algorithms to Tuberculosis Antibiotic Treatment Regimens

Joseph M. Cicchese, Elsje Pienaar, Denise E. Kirschner et al. · Cellular and Molecular Bioengineering · 2017 · 34 citations · Full text

Large-scale Global Optimization, Engineering, Optimization Algorithms +3

A multi-scale pipeline linking drug transcriptomics with pharmacokinetics predicts in vivo interactions of tuberculosis drugs

Joseph M. Cicchese, Awanti Sambarey, Denise E. Kirschner et al. · Scientific Reports · 2021 · 25 citations · Full text

Optimizing tuberculosis treatment efficacy: Comparing the standard regimen with Moxifloxacin-containing regimens

Maral Budak, Joseph M. Cicchese, Pauline Maiello et al. · PLoS Computational Biology · 2023 · 18 citations · Full text

World Health Organization, Antibiotic Adjuvant, Tuberculosis Prevention +20