Gaëtan Després

CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntington’s disease

Lydie Boussicault, Sandro Alves, Antonin Lamazière et al. · Brain · 2016 · 186 citations · Full text

Life Sciences, Biochemistry, Neuroscience +17

CYP46A1 gene therapy deciphers the role of brain cholesterol metabolism in Huntington’s disease

Radhia Kacher, Antonin Lamazière, Nicolas Heck et al. · Brain · 2019 · 112 citations · Full text

Life Sciences, Neurology, Neuroscience +15

Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia

Clévio Nóbrega, Liliana Mendonça, Adriana Marcelo et al. · Acta Neuropathologica · 2019 · 81 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Dendrogenin A Synergizes with Cytarabine to Kill Acute Myeloid Leukemia Cells In Vitro and In Vivo

Nizar Serhan, Pierre‐Luc Mouchel, Philippe de Médina et al. · Cancers · 2020 · 22 citations · Full text

Medicine, Oncology, Pharmacology +17

Lipidome variations of deep-sea vent shrimps according to acclimation pressure: A homeoviscous response?

Bruce Shillito, C. Desurmont, Dominique Barthélémy et al. · Deep Sea Research Part I Oceanographic Research Papers · 2020 · 19 citations · Full text

Life Sciences, Marine Biology, Marine Sciences +16