Hirotomo Machiyama

Clinical implications of monitoring nivolumab immunokinetics in non–small cell lung cancer patients

Akio Osa, Takeshi Uenami, Shohei Koyama et al. · JCI Insight · 2018 · 234 citations · Full text

Pharmacy, Immunology, Oncology +17

Lipid nanoparticles of Type-A CpG D35 suppress tumor growth by changing tumor immune-microenvironment and activate CD8 T cells in mice

Lisa Munakata, Yoshihiko Tanimoto, Akio Osa et al. · Journal of Controlled Release · 2019 · 48 citations · Full text

Life Sciences, Immunology, Oncology +17

Tumor-derived semaphorin 4A improves PD-1–blocking antibody efficacy by enhancing CD8 ⁺ T cell cytotoxicity and proliferation

Yujiro Naito, Shohei Koyama, Kentaro Masuhiro et al. · Science Advances · 2023 · 30 citations · Full text

Medicine, Immunology, Oncology +17