Charles G. Starr

Simulation-Guided Rational <i>de Novo</i> Design of a Small Pore-Forming Antimicrobial Peptide

Charles H. Chen, Charles G. Starr, Evan P. Troendle et al. · Journal of the American Chemical Society · 2019 · 122 citations · Full text

Engineering, Amino Acids, Peptide Engineering +19

Antimicrobial peptides are degraded by the cytosolic proteases of human erythrocytes

Charles G. Starr, William C. Wimley · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2017 · 98 citations · Full text

Cytosolic Proteases, Biochemistry, Peptide Library +9

Host Cell Interactions Are a Significant Barrier to the Clinical Utility of Peptide Antibiotics

Charles G. Starr, Jing He, William C. Wimley · ACS Chemical Biology · 2016 · 88 citations

Synthetic molecular evolution of host cell-compatible, antimicrobial peptides effective against drug-resistant, biofilm-forming bacteria

Charles G. Starr, Jenisha Ghimire, Shantanu Guha et al. · Proceedings of the National Academy of Sciences · 2020 · 68 citations · Full text

Engineering, Evolved Peptides, Antibiotic Adjuvant +20

Conformational Fine-Tuning of Pore-Forming Peptide Potency and Selectivity

Aram J. Krauson, O. Morgan Hall, Taylor Fuselier et al. · Journal of the American Chemical Society · 2015 · 67 citations · Full text

Proteinlipid Interaction, Protein Secretion, Peptide Engineering +18