Mikah S. Brandes

Loss of NRF2 leads to impaired mitochondrial function, decreased synaptic density and exacerbated age-related cognitive deficits

Jonathan A. Zweig, Maya Caruso, Mikah S. Brandes et al. · Experimental Gerontology · 2019 · 49 citations · Full text

Alzheimer's Disease, Aging, Mitochondrial Function +10

Loss of NRF2 accelerates cognitive decline, exacerbates mitochondrial dysfunction, and is required for the cognitive enhancing effects of Centella asiatica during aging

Jonathan A. Zweig, Mikah S. Brandes, Barbara H. Brumbach et al. · Neurobiology of Aging · 2020 · 32 citations · Full text

Lifespan Extension, Alzheimer's Disease, Aging +12

Prolonged Treatment with Centella asiatica Improves Memory, Reduces Amyloid-β Pathology, and Activates NRF2-Regulated Antioxidant Response Pathway in 5xFAD Mice

Jonathan A. Zweig, Mikah S. Brandes, Barbara H. Brumbach et al. · Journal of Alzheimer s Disease · 2021 · 32 citations · Full text

Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella asiatica Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized Clinical Trial

Kirsten M. Wright, Melissa Bollen, Jason David et al. · Antioxidants · 2022 · 31 citations · Full text

NRF2 Activation Ameliorates Oxidative Stress and Improves Mitochondrial Function and Synaptic Plasticity, and in A53T α-Synuclein Hippocampal Neurons

Mikah S. Brandes, Jonathan A. Zweig, Anita L. Tang et al. · Antioxidants · 2021 · 22 citations · Full text