Michael Hopp

A randomised controlled trial with prolonged‐release oral oxycodone and naloxone to prevent and reverse opioid‐induced constipation

Petra Leyendecker, Stefan Mueller‐Lissner, J. Nadstawek et al. · European Journal of Pain · 2008 · 255 citations

Nursing, Pharmacology, Pharmacotherapy +17

Prolonged release oxycodone–naloxone for treatment of severe restless legs syndrome after failure of previous treatment: a double-blind, randomised, placebo-controlled trial with an open-label extension

Claudia Trenkwalder, Heike Beneš, Ludger Grote et al. · The Lancet Neurology · 2013 · 225 citations

Medicine, Pharmacology, Pharmacotherapy +14

Analgesic Efficacy and Safety of Oxycodone in Combination With Naloxone as Prolonged Release Tablets in Patients With Moderate to Severe Chronic Pain

Dana Vondráčková, Petra Leyendecker, Michael Hopp et al. · Journal of Pain · 2008 · 211 citations

Nursing, Pharmacology, Pharmacotherapy +15

Fixed-ratio combination oxycodone/naloxone compared with oxycodone alone for the relief of opioid-induced constipation in moderate-to-severe noncancer pain

Karen H Simpson, Petra Leyendecker, Michael Hopp et al. · Current Medical Research and Opinion · 2008 · 179 citations

Medicine, Pharmacology, Pharmacotherapy +17

A randomized, double-blind, active-controlled, double-dummy, parallel-group study to determine the safety and efficacy of oxycodone/naloxone prolonged-release tablets in patients with moderate/severe, chronic cancer pain

Sam H. Ahmedzai, Friedemann Nauck, Gil Bar‐Sela et al. · Palliative Medicine · 2011 · 163 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17