Christine Hough

The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study

Paula D. James, Colleen Notley, Carol Hegadorn et al. · Blood · 2006 · 351 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Systemic delivery of an adenoviral vector encoding canine factor VIII results in short-term phenotypic correction, inhibitor development, and biphasic liver toxicity in hemophilia A dogs

A M Gallo-Penn, Pamela S. Shirley, J. Andrews et al. · Blood · 2001 · 112 citations · Full text

Veterinary Medicine, Infectious Diseases, Veterinary Pharmacology +14

Ex Vivo Gene Therapy for Hemophilia A That Enhances Safe Delivery and Sustained In Vivo Factor VIII Expression from Lentivirally Engineered Endothelial Progenitors

Hideto Matsui, Masaru Shibata, Brian D. Brown et al. · Stem Cells · 2007 · 105 citations · Full text

Pharmacy, Bioengineering, Hematology +17

Founder von Willebrand factor haplotype associated with type 1 von Willebrand disease

Lee A. O’Brien, Paula D. James, Maha Othman et al. · Blood · 2003 · 96 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Aberrant Splicing and Premature Termination of Transcription of the FVIII Gene as a Cause of Severe Canine Hemophilia A: Similarities with the Intron 22 Inversion Mutation in Human Hemophilia

Christine Hough, Seiki Kamisue, Cherie Cameron et al. · Thrombosis and Haemostasis · 2002 · 83 citations

Life Sciences, Genetics, Molecular Genetics +16