Priscila El Kazzi

A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase

Ashleigh Shannon, Véronique Fattorini, Bhawna Sama et al. · Nature Communications · 2022 · 110 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner

Lisa Bauer, Roberto Manganaro, Birgit Zonsics et al. · ACS Infectious Diseases · 2019 · 74 citations · Full text

Life Sciences, Infectious Diseases, Pharmacology +17

Structure–function analysis of the nsp14 N7–guanine methyltransferase reveals an essential role in <i>Betacoronavirus</i> replication

Natacha S. Ogando, Priscila El Kazzi, Jessika C. Zevenhoven-Dobbe et al. · Proceedings of the National Academy of Sciences · 2021 · 56 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +13

Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex

Daniel L. Hurdiss, Priscila El Kazzi, Lisa Bauer et al. · Science Advances · 2022 · 34 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Internal RNA 2′O-methylation in the HIV-1 genome counteracts ISG20 nuclease-mediated antiviral effect

Priscila El Kazzi, Nadia Rabah, Célia Chamontin et al. · Nucleic Acids Research · 2022 · 29 citations · Full text

Life Sciences, Immunology, Molecular Biology +17