Simon Bucher

A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen

Anaïs Michaut, Dounia Le Guillou, Caroline Moreau et al. · Toxicology and Applied Pharmacology · 2015 · 68 citations · Full text

Pharmacy, Pharmacology, Toxicology +14

Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity

Julien Allard, Simon Bucher, Julie Massart et al. · Cell Biology and Toxicology · 2020 · 60 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids

Hanbing Song, Simon Bucher, Katherine Rosenberg et al. · Nature Communications · 2022 · 57 citations · Full text

Medicine, Cancer Biology, Oncology +17

Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure

Simon Bucher, Dounia Le Guillou, Julien Allard et al. · Oxidative Medicine and Cellular Longevity · 2018 · 47 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo

Simon Bucher, Arnaud Tête, Normand Podechard et al. · Scientific Reports · 2018 · 46 citations · Full text

Veterinary Medicine, Pathobiology, Toxicology +17