Kayla Simeone

Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis

Yue Zhang, Faezeh Vasheghani, Yinghua Li et al. · Annals of the Rheumatic Diseases · 2014 · 414 citations

Life Sciences, Cell Biology, Molecular Medicine +17

Carboplatin response in preclinical models for ovarian cancer: comparison of 2D monolayers, spheroids, ex vivo tumors and in vivo models

Melica Nourmoussavi Brodeur, Kayla Simeone, Kim Leclerc-Deslauniers et al. · Scientific Reports · 2021 · 49 citations · Full text

Medicine, Oncology, Pharmacology +15

Microdissected Tissue vs Tissue Slices—A Comparative Study of Tumor Explant Models Cultured On-Chip and Off-Chip

Dina Dorrigiv, Kayla Simeone, Laudine Communal et al. · Cancers · 2021 · 29 citations · Full text

Engineering, Bioengineering, Oncology +14

Paraffin-embedding lithography and micro-dissected tissue micro-arrays: tools for biological and pharmacological analysis of <i>ex vivo</i> solid tumors

Kayla Simeone, Robin Guay-Lord, Mohammad Abdul Lateef et al. · Lab on a Chip · 2019 · 27 citations

Medicine, Bioengineering, Oncology +13

Modeling the Diversity of Epithelial Ovarian Cancer through Ten Novel Well Characterized Cell Lines Covering Multiple Subtypes of the Disease

Skye Alexandre Sauriol, Kayla Simeone, Lise Portelance et al. · Cancers · 2020 · 15 citations · Full text

Medicine, Cell Biology, Oncology +16