Probing Gene Expression in Live Cells, One Protein Molecule at a Time

Ji Yu, Jie Xiao, Xiaojia Ren, +2

Science

Molecular BiologyProtein MoleculeGene Expression ProfilingSingle Protein MoleculesLive Cells +16

Living Cells as Test Tubes

X. Sunney Xie, Ji Yu, Wei Yang

Science

MicroscopySurface-enhanced Raman ScatteringTest TubesCell CultureLight Scattering Spectroscopy +18

Investigating Intracellular Dynamics of FtsZ Cytoskeleton with Photoactivation Single-Molecule Tracking

Lili Niu, Ji Yu

Biophysical Journal

Biophysical ModelingSingle Molecule BiophysicsFtsz CytoskeletonNatural SciencesMolecular Biology +8

Germination proteins in the inner membrane of dormant <i>Bacillus subtilis</i> spores colocalize in a discrete cluster

Keren K. Griffiths, Jingqiao Zhang, Ann E. Cowan, +2

Molecular Microbiology

Protein SecretionBacteriologyDiscrete ClusterMolecular BiologyGermination Proteins +14

Factors Affecting Variability in Time between Addition of Nutrient Germinants and Rapid Dipicolinic Acid Release during Germination of Spores of <i>Bacillus</i> Species

Pengfei Zhang, Will Garner, Xuan Yi, +3

Journal of Bacteriology

BiologySimultaneous Nutrient GerminationSpore BiologyPlant-microbe InteractionExtremophile +9

Single-molecule tracking of small GTPase Rac1 uncovers spatial regulation of membrane translocation and mechanism for polarized signaling

Sulagna Das, Taofei Yin, Qingfen Yang, +3

Proceedings of the National Academy of Sciences

Polarized SignalingCell AdhesionMolecular BiologyCytoskeletonCellular Physiology +22

Investigating Sub-Spine Actin Dynamics in Rat Hippocampal Neurons with Super-Resolution Optical Imaging

Vedakumar Tatavarty, Eun‐Ji Kim, Vladimir Rodionov, +1

PLoS ONE

Sub-spine Actin DynamicsCytoskeletonStructural PlasticityOptogeneticsCellular Neurobiology +21

11,12-Epoxyeicosatrienoic acid (11,12-EET): structural determinants for inhibition of TNF-α-Induced VCAM-1 expression

John R. Falck, L. Manmohan Reddy, Y. Krishna Reddy, +5

Bioorganic & Medicinal Chemistry Letters

Tnf-α-induced Vcam-1 ExpressionMolecular Pharmacology11,12-Epoxyeicosatrienoic AcidBiochemistryStructural Determinants +2

Fast rebinding increases dwell time of Src homology 2 (SH2)-containing proteins near the plasma membrane

Dongmyung Oh, Mari Ogiue‐Ikeda, Joshua A. Jadwin, +3

Proceedings of the National Academy of Sciences

Protein SecretionMolecular BiologyCellular PhysiologyDwell TimeProtein Folding +24

Single-molecule imaging of translational output from individual RNA granules in neurons

Vedakumar Tatavarty, Marius F. Ifrim, Mikhail K. Levin, +4

Molecular Biology of the Cell

Translational OutputEngineeringMolecular BiologyCytoskeletonOptogenetics +18