Kathleen Graham

Hepatocytes direct the formation of a pro-metastatic niche in the liver

Jae W. Lee, Meredith L. Stone, Paige M. Porrett et al. · Nature · 2019 · 407 citations · Full text

Hepatology, Liver Physiology, Pro-metastatic Niche +10

Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal

Mingen Liu, Roddy S. O’Connor, Sophie Trefely et al. · Nature Immunology · 2019 · 278 citations

Immunology, Cell Death, Metabolic Remodeling +17

IFNγ and CCL2 Cooperate to Redirect Tumor-Infiltrating Monocytes to Degrade Fibrosis and Enhance Chemotherapy Efficacy in Pancreatic Carcinoma

Kristen B. Long, Whitney L. Gladney, Graham M. Tooker et al. · Cancer Discovery · 2016 · 241 citations · Full text

Genetically Engineered Mouse Models of Pancreatic Cancer: The KPC Model (<i>LSL‐Kras^G12D/+;LSL‐Trp53^R172H/+;Pdx‐1‐Cre</i>), Its Variants, and Their Application in Immuno‐oncology Drug Discovery

Jae W. Lee, Chad A. Komar, Fee Bengsch et al. · Current Protocols in Pharmacology · 2016 · 196 citations · Full text

A rational mouse model to detect on-target, off-tumor CAR T cell toxicity

Mauro Castellarin, Caroline Sands, Tong Da et al. · JCI Insight · 2020 · 91 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +20