Daniela Bumbaca Yadav

Mechanisms of Acquired Resistance to Trastuzumab Emtansine in Breast Cancer Cells

Guangmin Li, Jun Guo, Ben‐Quan Shen et al. · Molecular Cancer Therapeutics · 2018 · 184 citations

Medicine, Oncology, Pharmacology +17

Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer’s disease

Gai Ayalon, Seung-Hye Lee, Oskar Adolfsson et al. · Science Translational Medicine · 2021 · 111 citations · Full text

Life Sciences, Neurology, Neuroscience +16

In vitro model for predicting bioavailability of subcutaneously injected monoclonal antibodies

Hanne Kinnunen Bown, Catherine Bonn, Stefan T. Yohe et al. · Journal of Controlled Release · 2018 · 87 citations

Pharmacy, Pharmaceutics, Pharmacokinetics +14

Evaluating the Use of Antibody Variable Region (Fv) Charge as a Risk Assessment Tool for Predicting Typical Cynomolgus Monkey Pharmacokinetics

Daniela Bumbaca Yadav, Vikas Sharma, C. Andrew Boswell et al. · Journal of Biological Chemistry · 2015 · 83 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization of antibody uptake in brain

Kapil Gadkar, Daniela Bumbaca Yadav, Joy Yu Zuchero et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2016 · 56 citations

Pharmacy, Pharmacokinetics, Pharmacology +16