Birgitt Gutbier

The NLRP3 Inflammasome Is Differentially Activated by Pneumolysin Variants and Contributes to Host Defense in Pneumococcal Pneumonia

Martin Witzenrath, Florence Pache, D. Lorenz et al. · The Journal of Immunology · 2011 · 252 citations · Full text

Veterinary Medicine, Infectious Diseases, Microbiology +17

Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia

Martin Witzenrath, Birgitt Gutbier, Andreas C. Hocke et al. · Critical Care Medicine · 2006 · 140 citations

Veterinary Medicine, Infectious Diseases, Inflammation +16

Systemic use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia*

Martin Witzenrath, Bernd Schmeck, Jan M. Doehn et al. · Critical Care Medicine · 2009 · 120 citations

Medicine, Infectious Diseases, Pharmacology +15

<i>Streptococcus pneumoniae</i> Stimulates a STING- and IFN Regulatory Factor 3-Dependent Type I IFN Production in Macrophages, which Regulates RANTES Production in Macrophages, Cocultured Alveolar Epithelial Cells, and Mouse Lungs

Uwe Koppe, Katrin Högner, Jan-Moritz Doehn et al. · The Journal of Immunology · 2011 · 112 citations

Veterinary Medicine, Immunology, Microbiology +17

Antibiotic treatment–induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia

Oliver Robak, Markus M. Heimesaat, Andrey Kruglov et al. · Journal of Clinical Investigation · 2018 · 106 citations · Full text

Life Sciences, Immunology, Microbiology +16