Ronald A.M. Buijsen

Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome

Chantal Sellier, Ronald A.M. Buijsen, Fang He et al. · Neuron · 2017 · 244 citations · Full text

Life Sciences, Genetics, Neuroscience +14

AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome

Josien Levenga, Shigemi Hayashi, Femke M.S. de Vrij et al. · Neurobiology of Disease · 2011 · 120 citations

Medicine, Pharmacology, Pharmacotherapy +4

Presence of inclusions positive for polyglycine containing protein, FMRpolyG, indicates that repeat-associated non-AUG translation plays a role in fragile X-associated primary ovarian insufficiency

Ronald A.M. Buijsen, Jenny A. Visser, P. Kramer et al. · Human Reproduction · 2015 · 103 citations · Full text

Medicine, Genetics, Molecular Genetics +4

Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice

Ilse Gantois, Andreea Pop, Celine de Esch et al. · Behavioural Brain Research · 2012 · 96 citations

Medicine, Neuroscience, Pharmacology +7

Rescue of dendritic spine phenotype in Fmr1 KO mice with the mGluR5 antagonist AFQ056/Mavoglurant

Andreea Pop, Josien Levenga, Celine de Esch et al. · Psychopharmacology · 2012 · 89 citations

Life Sciences, Neurobiology, Neuroscience +12