Rob De Vreese

Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models

Yves Depetter, Silke Geurs, Rob De Vreese et al. · International Journal of Cancer · 2019 · 90 citations · Full text

Design, Synthesis, and Antiviral Evaluation of Purine-β-lactam and Purine-aminopropanol Hybrids

Matthias D’hooghe, Karen Mollet, Rob De Vreese et al. · Journal of Medicinal Chemistry · 2012 · 65 citations

Bioorganic Chemistry, Promising Lead Structures, Antiviral Drug +19

Converting bulk sugars into prebiotics: semi-rational design of a transglucosylase with controlled selectivity

Tom Verhaeghe, Karel De Winter, Magali Berland et al. · Chemical Communications · 2016 · 44 citations

Potent and selective HDAC6 inhibitory activity of N-(4-hydroxycarbamoylbenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorenes as novel sulfur analogues of Tubastatin A

Rob De Vreese, Tom Verhaeghe, Tom Desmet et al. · Chemical Communications · 2013 · 34 citations

Combinatorial Chemistry, Medicinal Chemistry, Sulfur Analogues +14

Synthesis of novel curcuminoids accommodating a central β-enaminone motif and their impact on cell growth and oxidative stress

Rob De Vreese, Charlotte Grootaert, Sander D’hoore et al. · European Journal of Medicinal Chemistry · 2016 · 32 citations

Biochemistry, Medicine, Novel Curcuminoids +5