Rob De Vreese

Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models

Yves Depetter, Silke Geurs, Rob De Vreese et al. · International Journal of Cancer · 2019 · 92 citations · Full text

Medicine, Oncology, Pharmacology +12

Design, Synthesis, and Antiviral Evaluation of Purine-β-lactam and Purine-aminopropanol Hybrids

Matthias D’hooghe, Karen Mollet, Rob De Vreese et al. · Journal of Medicinal Chemistry · 2012 · 65 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Converting bulk sugars into prebiotics: semi-rational design of a transglucosylase with controlled selectivity

Tom Verhaeghe, Karel De Winter, Magali Berland et al. · Chemical Communications · 2016 · 45 citations

Life Sciences, Biochemistry, Biotechnology +17

Potent and selective HDAC6 inhibitory activity of N-(4-hydroxycarbamoylbenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorenes as novel sulfur analogues of Tubastatin A

Rob De Vreese, Tom Verhaeghe, Tom Desmet et al. · Chemical Communications · 2013 · 34 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Synthesis of Potent and Selective HDAC6 Inhibitors Bearing a Cyclohexane‐ or Cycloheptane‐Annulated 1,5‐Benzothiazepine Scaffold

Rob De Vreese, Lisa M. Galle, Yves Depetter et al. · Chemistry - A European Journal · 2016 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9