Mark Tremelling

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

Miles Parkes, Jeffrey C. Barrett, Natalie J. Prescott et al. · Nature Genetics · 2007 · 1.2K citations · Full text

Chronic Inflammatory Diseases, Disease Susceptibility, Cell Autophagy +13

Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study

Nicholas A. Kennedy, Graham Heap, Harry Green et al. · ˜The œLancet. Gastroenterology & hepatology · 2019 · 655 citations · Full text

Inflammation, Active Luminal Crohn, Anti-tnf Treatment Failure +9

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

Sheila Fisher, Mark Tremelling, Carl A. Anderson et al. · Nature Genetics · 2008 · 421 citations · Full text

Chronic Inflammatory Diseases, Genetics, Pathogenesis +9

HLA-DQA1*05 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn’s Disease

Aleksejs Sazonovs, Nicholas A. Kennedy, Loukas Moutsianas et al. · Gastroenterology · 2019 · 385 citations · Full text

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes

Yukihide Momozawa, Julia Dmitrieva, Emilie Théâtre et al. · Nature Communications · 2018 · 238 citations · Full text