Harmen J.G. van de Werken

Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells

Jessica Zuin, Jesse R. Dixon, Michael I. J. A. van der Reijden et al. · Proceedings of the National Academy of Sciences · 2013 · 820 citations

Life Sciences, Genetics, Molecular Biology +17

eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription

Carlos A. Melo, Jarno Drost, Patrick J. Wijchers et al. · Molecular Cell · 2012 · 532 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Robust 4C-seq data analysis to screen for regulatory DNA interactions

Harmen J.G. van de Werken, Gilad Landan, Sjoerd J.B. Holwerda et al. · Nature Methods · 2012 · 408 citations

Life Sciences, Genetics, Molecular Biology +16

The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies

Lindsay Angus, Marcel Smid, Saskia M. Wilting et al. · Nature Genetics · 2019 · 333 citations · Full text

Medicine, Genetics, Molecular Genetics +16

The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA

Erik Splinter, Elzo de Wit, Elphège P. Nora et al. · Genes & Development · 2011 · 304 citations · Full text

Life Sciences, Genetics, Molecular Biology +17