Thomas M. Koenig

Kilogram-scale prexasertib monolactate monohydrate synthesis under continuous-flow CGMP conditions

Kevin P. Cole, Jennifer McClary Groh, Martin D. Johnson et al. · Science · 2017 · 298 citations · Full text

Engineering, Chemical Engineering, Manufacturing Engineering +17

Conjugate reduction of polyfunctional α,β-unsaturated carbonyl compounds using [(Ph3P)CuH]6. Compatibility with halogen, sulfonate, and γ-oxygen and sulfur substituents

Thomas M. Koenig, John F. Daeuble, Donna M. Brestensky et al. · Tetrahedron Letters · 1990 · 81 citations

Natural Sciences, Chemical Engineering, Chemistry +11

Vinyl aryl ethers from copper-catalyzed coupling of vinyl halides and phenols

Zhonghui Wan, C. David Jones, Thomas M. Koenig et al. · Tetrahedron Letters · 2003 · 77 citations

Natural Sciences, Chemistry, Catalysis +9

Palladium-Catalyzed Hydroarylation of Propiolamides. A Regio- and Stereocontrolled Method for Preparing 3,3-Diarylacrylamides

Lynne A. Hay, Thomas M. Koenig, Francis O. Ginah et al. · The Journal of Organic Chemistry · 1998 · 71 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

A convenient method for preparing enantiomerically pure norfluoxetine, fluoxetine and tomoxetine

Thomas M. Koenig, David Mitchell · Tetrahedron Letters · 1994 · 61 citations

Pharmacy, Medicinal Chemistry, Pharmacology +2