Chenchen Han

Targeted inhibition of GRK2 kinase domain by CP-25 to reverse fibroblast-like synoviocytes dysfunction and improve collagen-induced arthritis in rats

Chenchen Han, Yifan Li, Yuwen Zhang et al. · Acta Pharmaceutica Sinica B · 2021 · 74 citations · Full text

Medicine, Biochemistry, Pharmacology +15

GRK2 overexpression inhibits IGF1-induced proliferation and migration of human hepatocellular carcinoma cells by downregulating EGR1

Yang Ma, Chenchen Han, Qiong Huang et al. · Oncology Reports · 2016 · 49 citations · Full text

Medicine, Molecular Biology, Oncology +14

Insulin-like growth factor-binding protein-3 inhibits IGF-1-induced proliferation of human hepatocellular carcinoma cells by controlling bFGF and PDGF autocrine/paracrine loops

Yang Ma, Chenchen Han, Yifan Li et al. · Biochemical and Biophysical Research Communications · 2016 · 42 citations

Life Sciences, Cell Biology, Oncology +12

CP-25 inhibits PGE2-induced angiogenesis by down-regulating EP4/AC/cAMP/PKA-mediated GRK2 translocation

Chenchen Han, Qian Liu, Yu Zhang et al. · Clinical Science · 2020 · 38 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Immunomodulatory Effects of CP-25 on Splenic T Cells of Rats with Adjuvant Arthritis

Yang Wang, Chenchen Han, Dongqian Cui et al. · Inflammation · 2018 · 25 citations

Life Sciences, Immunology, Cellular Immunology +15