Concepedia

Changkai Jia

CJ

4

Publications

105

Citations

4

H-Index

2022

Active since

Affiliations

Beijing Proteome Research Center(Current)

Changkai Jia is an author at Beijing Proteome Research Center specializing in medicine, cell biology, and drug discovery.

Top concepts

Publications per year

2022–2024

4

Publications

4

Discovery of highly potent and selective KRASG12C degraders by VHL-recruiting PROTACs for the treatment of tumors with KRASG12C-Mutation

Ning Yang, Zhiya Fan, Shiyang Sun et al. · European Journal of Medicinal Chemistry · 2023 · 33 citations

, , +8

Discovery of highly potent and selective CRBN-recruiting EGFRL858R/T790M degraders in vivo

Wenjuan Zhang, Pengyun Li, Shiyang Sun et al. · European Journal of Medicinal Chemistry · 2022 · 30 citations

, , +5

Discovery of novel exceptionally potent and orally active c-MET PROTACs for the treatment of tumors with MET alterations

Pengyun Li, Changkai Jia, Zhiya Fan et al. · Acta Pharmaceutica Sinica B · 2023 · 26 citations · Full text

Novel potent molecular glue degraders against broad range of hematological cancer cell lines via multiple neosubstrates degradation

Pengyun Li, Xiaotong Hu, Zhiya Fan et al. · Journal of Hematology & Oncology · 2024 · 16 citations · Full text

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