Jon Minford

Isolation of intercalator-dependent protein-linked DNA strand cleavage activity from cell nuclei and identification as topoisomerase II

Jon Minford, Yves Pommier, Jan Filipski et al. · Biochemistry · 1986 · 141 citations

Life Sciences, Biochemistry, Molecular Biology +9

Effects of the DNA intercalators 4'-(9-acridinylamino)methanesulfon-m-anisidide and 2-methyl-9-hydroxyellipticinium on topoisomerase II mediated DNA strand cleavage and strand passage

Yves Pommier, Jon Minford, Ronald E. Schwartz et al. · Biochemistry · 1985 · 127 citations

Life Sciences, Molecular Biology, Dna Repair +12

Enhancement of the DNA breakage and cytotoxic effects of intercalating agents by treatment with sublethal doses of 1-beta-D-arabinofuranosylcytosine or hydroxyurea in L1210 cells.

Jon Minford, Donna Kerrigan, Margaret Nichols et al. · PubMed · 1984 · 27 citations

Life Sciences, Cancer Biology, Molecular Biology +17

Enhancement of intercalator-induced deoxyribonucleic acid scission and cytotoxicity in murine leukemia cells treated with 5-azacytidine

L. A. Zwelling, Jon Minford, Margaret Nichols et al. · Biochemical Pharmacology · 1984 · 17 citations

Pharmacy, Cancer Biology, Oncology +9