Yelena Losev

Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer’s disease-like symptoms in animal model

Guru KrishnaKumar Viswanathan, Dana Shwartz, Yelena Losev et al. · Cellular and Molecular Life Sciences · 2019 · 62 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Alzheimer's Disease +13

Differential effects of putative N-glycosylation sites in human Tau on Alzheimer’s disease-related neurodegeneration

Yelena Losev, Moran Frenkel‐Pinter, Malak Abu-Hussien et al. · Cellular and Molecular Life Sciences · 2020 · 50 citations · Full text

Glycoproteomics, Neurodegenerative Diseases, Molecular Neuroscience +12

Novel model of secreted human tau protein reveals the impact of the abnormal N-glycosylation of tau on its aggregation propensity

Yelena Losev, Ashim Paul, Moran Frenkel‐Pinter et al. · Scientific Reports · 2019 · 46 citations · Full text

Integrating in vitro and in silico approaches to evaluate the “dual functionality” of palmatine chloride in inhibiting and disassembling Tau-derived VQIVYK peptide fibrils

Esraa Haj, Yelena Losev, Edward Pichinuk et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2018 · 40 citations

Biochemistry, Silico Approaches, Protein Folding +12

Altered protein glycosylation predicts Alzheimer's disease and modulates its pathology in disease model Drosophila

Moran Frenkel‐Pinter, Shiri Stempler, Sharon Tal-Mazaki et al. · Neurobiology of Aging · 2017 · 26 citations

Glycoproteomics, Neurodegenerative Diseases, Alzheimer's Disease +15