Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds

S. Tuuli Karhu, Mika J. Välimäki, Mikael Jumppanen, +9

Archives of Toxicology

Synthesis, Identification, and Structure–Activity Relationship Analysis of GATA4 and NKX2-5 Protein–Protein Interaction Modulators

Mikael Jumppanen, Sini M. Kinnunen, Mika J. Välimäki, +8

Journal of Medicinal Chemistry

A Simple Method for Improving the Spatial Resolution in Infrared Laser Ablation Mass Spectrometry Imaging

Juha-Pekka Hieta, Anu Vaikkinen, Samuli Auno, +6

Journal of the American Society for Mass Spectrometry

Adenosine analogs bearing phosphate isosteres as human MDO1 ligands

Yuezhou Zhang, Mikael Jumppanen, Mirko M. Maksimainen, +8

Bioorganic & Medicinal Chemistry

OligonucleotideBiochemistryAdenosine Analogs

Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on α-Synuclein Mouse Models of Parkinson’s Disease

Tommi Kilpeläinen, Henri T. Pätsi, Reinis Svarcbahs, +10

Journal of Medicinal Chemistry

Prolyl oligopeptidase inhibition reduces alpha‐synuclein aggregation in a cellular model of multiple system atrophy

Hengjing Cui, Tommi Kilpeläinen, Lydia Zouzoula, +7

Journal of Cellular and Molecular Medicine

Removal of proteinase K resistant αSyn species does not correlate with cell survival in a virus vector-based Parkinson's disease mouse model

Tony Eteläinen, Tommi Kilpeläinen, Adele Ignatius, +5

Neuropharmacology

5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein–Protein Interaction-Derived Functions

Henri T. Pätsi, Tommi Kilpeläinen, Mikael Jumppanen, +14

Journal of Medicinal Chemistry