Lorraine Elkerbout

The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity

Jibran A. Wali, Dieter Rondas, Mark McKenzie et al. · Cell Death and Disease · 2014 · 109 citations · Full text

Life Sciences, Cell Biology, Endocrinology +17

Deficiency in Type I Interferon Signaling Prevents the Early Interferon–Induced Gene Signature in Pancreatic Islets but Not Type 1 Diabetes in NOD Mice

Hong Sheng Quah, Socorro Miranda‐Hernandez, Aimee Khoo et al. · Diabetes · 2013 · 36 citations · Full text

Life Sciences, Endocrinology, Immunology +15

Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes

Yuxing Zhao, Nicholas A. Scott, Stacey Fynch et al. · Diabetologia · 2014 · 35 citations

Life Sciences, Cell Biology, Immunology +17

The Protective Effects of CD39 Overexpression in Multiple Low-Dose Streptozotocin–Induced Diabetes in Mice

Joanne SJ Chia, Jennifer L. McRae, Helen E. Thomas et al. · Diabetes · 2013 · 34 citations · Full text

Medicine, Endocrinology, Pharmacology +16

Activation of the NLRP3 Inflammasome Complex is Not Required for Stress-Induced Death of Pancreatic Islets

Jibran A. Wali, Esteban N. Gurzov, Stacey Fynch et al. · PLoS ONE · 2014 · 31 citations · Full text

Life Sciences, Cell Biology, Endocrinology +17