Alexandra Mendes-Madeira

Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium

Guylène Le Meur, Knut Stieger, Alexander J. Smith et al. · Gene Therapy · 2006 · 203 citations

Medicine, Ophthalmology, Veterinary Ophthalmology +16

Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors

Knut Stieger, Guylène Le Meur, Françoise Lasne et al. · Molecular Therapy · 2006 · 108 citations · Full text

Medicine, Molecular Biology, Ophthalmology +12

Biodistribution of rAAV Vectors Following Intraocular Administration: Evidence for the Presence and Persistence of Vector DNA in the Optic Nerve and in the Brain

Nathalie Provost, Guylène Le Meur, Michel Weber et al. · Molecular Therapy · 2004 · 87 citations · Full text

Medicine, Neuroscience, Ophthalmology +16

Detection of Intact rAAV Particles up to 6 Years After Successful Gene Transfer in the Retina of Dogs and Primates

Knut Stieger, Josef Schroeder, Nathalie Provost et al. · Molecular Therapy · 2008 · 83 citations · Full text

Medicine, Molecular Biology, Ophthalmology +15

Subretinal Delivery of Recombinant AAV Serotype 8 Vector in Dogs Results in Gene Transfer to Neurons in the Brain

Knut Stieger, Marie-Anne Colle, Laurence Dubreil et al. · Molecular Therapy · 2008 · 74 citations · Full text

Medicine, Molecular Biology, Ophthalmology +17