Xiangbao Meng

SHP2 inhibition triggers anti-tumor immunity and synergizes with PD-1 blockade

Mingxia Zhao, Wenjie Guo, Yuanyuan Wu et al. · Acta Pharmaceutica Sinica B · 2018 · 177 citations · Full text

TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-Butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice

Mingming Zhao, Lin Zhao, Xuelian Xiong et al. · Gastroenterology · 2020 · 125 citations

Inflammation, Intestinal Microbes, Hepatology +14

Inhibiting the NLRP3 Inflammasome Activation with MCC950 Ameliorates Diabetic Encephalopathy in db/db Mice

Yadong Zhai, Xiangbao Meng, Tianyuan Ye et al. · Molecules · 2018 · 117 citations · Full text

Immunology, Immune Regulation, Pathology +27

Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy

Mingming Zhao, Haoran Wei, Chenze Li et al. · Nature Communications · 2022 · 94 citations · Full text

Aconitine-induced Ca2+ overload causes arrhythmia and triggers apoptosis through p38 MAPK signaling pathway in rats

Guibo Sun, Hong Sun, Xiangbao Meng et al. · Toxicology and Applied Pharmacology · 2014 · 93 citations

Aconitine-induced Ca2+ Overload, Cardiac Muscle, Heart Failure +9