Mathew J. Wyvratt

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Active since

1991

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Mathew J. Wyvratt is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicinal chemistry, pharmacology, and drug discovery.

Publications per year

1991–2010

Publications

Preparation and in vitro activities of naphthyl and indolyl ether derivatives of the FK-506 related immunosuppressive macrolide ascomycin

Frederick Wong, Mary Jo Staruch, Greg Wiederrecht et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 37 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

Discovery of a novel class of biphenyl pyrazole sodium channel blockers for treatment of neuropathic pain

Sriram Tyagarajan, Prasun K. Chakravarty, Bishan Zhou et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 21 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Substituted biaryl pyrazoles as sodium channel blockers

Sriram Tyagarajan, Prasun K. Chakravarty, Bishan Zhou et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 18 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Substituted biaryl oxazoles, imidazoles, and thiazoles as sodium channel blockers

Sriram Tyagarajan, Prasun K. Chakravarty, Bishan Zhou et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 13 citations · Full text

Natural Sciences, Medicinal Chemistry, Pharmacology +14

1-(Substituted)benzyl-5-aminoimidazole-4-carboxamides are potent orally active inhibitors ofTrypanosoma cruzi in mice

John C. Chabala, Virginia B. Waits, Theodore J. Ikeler et al. · Cellular and Molecular Life Sciences · 1991 · 10 citations

Medicine, Medicinal Chemistry, Pharmacology +8

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