Katherine D. LaClair

Tdp-43 cryptic exons are highly variable between cell types

Yun Ha Jeong, Jonathan P. Ling, Sophie Lin et al. · Molecular Neurodegeneration · 2017 · 126 citations · Full text

Cryptic exon incorporation occurs in Alzheimer’s brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43

Mingkuan Sun, William R. Bell, Katherine D. LaClair et al. · Acta Neuropathologica · 2017 · 110 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Molecular Neuroscience +13

Depletion of TDP-43 decreases fibril and plaque β-amyloid and exacerbates neurodegeneration in an Alzheimer’s mouse model

Katherine D. LaClair, Aneesh Donde, Jonathan P. Ling et al. · Acta Neuropathologica · 2016 · 95 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Tdp-43 Decreases Fibril +10

Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice

Katherine D. LaClair, Kebreten F. Manaye, Dexter L. Lee et al. · Molecular Neurodegeneration · 2013 · 84 citations · Full text

Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS

Katherine D. LaClair, Qihui Zhou, Meike Michaelsen et al. · Acta Neuropathologica · 2020 · 70 citations · Full text