Concepedia
Author
Jiajun Yap
Also Known As
Jiajun Yap, Yap Jiajun, Yap, Jiajun
17
Publications
694
Citations
7
H-Index
0
Concepts
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All Concepts
5
165
The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutants
Jimin Yuan, Wan Hwa Ng, Paula Yeng Po Lam, +8
Oncogene
2018
57
Activating mutations in MEK1 enhance homodimerization and promote tumorigenesis
Jimin Yuan, Wan Hwa Ng, Zizi Tian, +4
Science Signaling
53
The stability of R-spine defines RAF inhibitor resistance: A comprehensive analysis of oncogenic BRAF mutants with in-frame insertion of αC-β4 loop
Jiajun Yap, R. N. V. Krishna Deepak, Zizi Tian, +11
Science Advances
2021
26
The AMPK inhibitor overcomes the paradoxical effect of RAF inhibitors through blocking phospho–Ser-621 in the C terminus of CRAF
Jimin Yuan, Wan Hwa Ng, Jiajun Yap, +4
Journal of Biological Chemistry
BRAF(V600E) mutation together with loss of Trp53 or pTEN drives the origination of hairy cell leukemia from B-lymphocytes
Jiajun Yap, Jimin Yuan, Wan Hwa Ng, +11
Molecular Cancer
2023
12
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