Dervla T. Isaac

MavN is a <i>Legionella pneumophila</i> vacuole-associated protein required for efficient iron acquisition during intracellular growth

Dervla T. Isaac, Rita K. Laguna, N Valtz et al. · Proceedings of the National Academy of Sciences · 2015 · 71 citations · Full text

Microbial Pathogens, Iron Metabolism, Intracellular Growth +18

Macrophage cell death and transcriptional response are actively triggered by the fungal virulence factor <scp>C</scp>bp1 during <scp><i>H</i></scp>. <i>capsulatum</i> infection

Dervla T. Isaac, Charlotte Berkes, Bevin C. English et al. · Molecular Microbiology · 2015 · 43 citations · Full text

Microbial Pathogens, Fungal Cell Biology, Apoptosis +20

The 3-Hydroxy-Methylglutaryl Coenzyme A Lyase<i>HCL1</i>Is Required for Macrophage Colonization by Human Fungal Pathogen Histoplasma capsulatum

Dervla T. Isaac, Alison Coady, Nancy Van Prooyen et al. · Infection and Immunity · 2012 · 34 citations · Full text

Industrial Mycology, Biochemistry, Fungal Cell Biology +12

PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models

Chun Wai Wong, Christos Evangelou, Kieran N. Sefton et al. · Nature Communications · 2023 · 34 citations · Full text

The iron-regulated vacuolar <i>Legionella pneumophila</i> MavN protein is a transition-metal transporter

Eric T. Christenson, Dervla T. Isaac, K Yoshida et al. · Proceedings of the National Academy of Sciences · 2019 · 31 citations · Full text