Generation of uniform liver spheroids from human pluripotent stem cells for imaging-based drug toxicity analysis

Gyunggyu Lee, Hyemin Kim, Ji Young Park, +10

Biomaterials

Induced Pluripotent Stem CellEngineeringUniform Liver SpheroidsLiver PhysiologyStem Cell Toxicology +9

Development of human pluripotent stem cell-derived hepatic organoids as an alternative model for drug safety assessment

Hyemin Kim, Ilkyun Im, Jang Su Jeon, +12

Biomaterials

Liver FunctionBiomedical EngineeringAlternative ModelDrug Safety AssessmentRegenerative Medicine +21

Prediction of Drug-Induced Liver Injury in HepG2 Cells Cultured with Human Liver Microsomes

Jong Min Choi, Soo Jin Oh, Ji-Yoon Lee, +5

Chemical Research in Toxicology

ImmunologyToxicological MechanismToxicologyHepatotoxicityHuman Metabolism +19

Role of the CYP3A4-mediated 11,12-epoxyeicosatrienoic acid pathway in the development of tamoxifen-resistant breast cancer

Nguyễn Thị Thùy Phương, Ji Won Kim, Jang Su Jeon, +5

Oncotarget

Breast OncologyOncologyTamoxifen-resistant Breast CancerMedicineCytochrome P450 +10

Hepatic expression of cytochrome P450 in Zucker diabetic fatty rats

So Young Park, Chung Hyeon Kim, Ji Yoon Lee, +6

Food and Chemical Toxicology

Metabolic SyndromeHepatologyBiochemistryMedicineLiver Physiology +11

Heterogeneity of glutamine metabolism in acquired-EGFR-TKI-resistant lung cancer

Suntae Kim, Jang Su Jeon, Yong June Choi, +3

Life Sciences

Glutamine MetabolismMedicineBronchial NeoplasmLung CancerCancer Metabolism +3

Quasi-Irreversible Inhibition of CYP2D6 by Berberine

Ha Gyeong Kim, Han Sol Lee, Jang Su Jeon, +12

Pharmaceutics

Age-Related Changes in Sulfur Amino Acid Metabolism in Male C57BL/6 Mice

Jang Su Jeon, Jeong‐Ja Oh, Hui Chan Kwak, +5

Biomolecules & Therapeutics

Male C57bl/6 MiceMetabolomic ProfilingBiogerontologyRedox BiologyOxidative Stress +17

Discovery of enantioselectivity of urea inhibitors of soluble epoxide hydrolase

Manoj Manickam, Thanigaimalai Pillaiyar, Pulla Reddy Boggu, +7

European Journal of Medicinal Chemistry

BiochemistryNatural SciencesBiocatalysisMedicineEnzyme Catalysis +5

Metabolic characterization of meso-dihydroguaiaretic acid in liver microsomes and in mice

Jang Su Jeon, Soo Jin Oh, Ji Yoon Lee, +4

Food and Chemical Toxicology

Energy MetabolismMeso-dihydroguaiaretic AcidBiochemistryMedicineLiver Physiology +12