Matthias Birtel

An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors

Katharina Reinhard, Benjamin Rengstl, Petra Oehm et al. · Science · 2020 · 507 citations

Medicine, Immunology, Oncology +17

CRISPR/Cas9-mediated TGFβRII disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells in vitro

Khadijeh Alishah, Matthias Birtel, Elham Masoumi et al. · Journal of Translational Medicine · 2021 · 44 citations · Full text

Life Sciences, Immunology, Oncology +17

Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences

Aswin Mangerich, Małgorzata Dębiak, Matthias Birtel et al. · Toxicology Letters · 2015 · 39 citations

Life Sciences, Biochemistry, Molecular Biology +7

An optimized single chain TCR scaffold relying on the assembly with the native CD3-complex prevents residual mispairing with endogenous TCRs in human T-cells

Diana Knies, Sebastian Klobuch, Shao‐An Xue et al. · Oncotarget · 2016 · 33 citations · Full text

Medicine, Hematology, Immunology +11

A TCR-like CAR Promotes Sensitive Antigen Recognition and Controlled T-cell Expansion Upon mRNA Vaccination

Matthias Birtel, Ralf-Holger Voss, Katharina Reinhard et al. · Cancer Research Communications · 2022 · 20 citations · Full text

Medicine, Immunology, Oncology +17